Description

(S)-Pyrrolidine-2-Carboxylic Acid (4-Fluoro-Phenyl)-Amide is a high-purity chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Protease Inhibitor Synthesis: Used in the development of inhibitors targeting specific enzymes due to its pyrrolidine carboxylic acid amide scaffold.
• Agrochemical Research: Serves as a precursor in the design and synthesis of new-generation pesticides and herbicides.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands for asymmetric catalysis.
• Peptidomimetics: Integral for constructing peptidomimetic compounds in medicinal chemistry programs.
• Chemical Biology Probes: Used to develop molecular probes for studying biological pathways and protein function.

Basic Information

Product Name	(S)-Pyrrolidine-2-Carboxylic Acid (4-Fluoro-Phenyl)-Amide
CAS No.	367521-34-4
Molecular Formula	C11H13FN2O
Molecular Weight	208.23 g/mol
Synonyms	(S)-2-Pyrrolidinecarboxamide, N-(4-fluorophenyl)-; (S)-N-(4-Fluorophenyl)pyrrolidine-2-carboxamide; L-Proline, 1-[(4-fluorophenyl)amino]-1-oxo-; (S)-1-(4-Fluorophenylcarbamoyl)pyrrolidine-2-carboxylic acid (tautomer); 4-Fluoro-N-[(2S)-pyrrolidin-2-ylcarbonyl]aniline; (S)-Pyrrolidine-2-carboxylic acid (4-fluoro-phenyl)-amide; (S)-Pyrrolidine-2-carboxylic acid 4-fluoroanilide
EINECS	Contact for details

Quality Control

Our (S)-Pyrrolidine-2-Carboxylic Acid (4-Fluoro-Phenyl)-Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for research and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.