Description

2-Buten-1-One, 2,3-Difluoro-1-Phenyl-, (2Z)- (9Ci) is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. Its core value lies in the precise introduction of fluorine atoms and an α,β-unsaturated ketone moiety into target molecules, enabling the fine-tuning of physical, chemical, and biological properties. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced metabolic stability, bioavailability, and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in constructing advanced intermediates for novel herbicides, fungicides, and insecticides, where fluorine atoms improve efficacy and environmental profile.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials requiring specific fluorinated segments.
• Chemical Research & Development: Employed in academic and industrial labs for methodology development, such as cycloaddition reactions and catalytic asymmetric synthesis.
• Fluorine Chemistry Exploration: Acts as a model substrate for studying the reactivity and transformation of vicinal difluoro olefins in complex molecular settings.

Basic Information

Product Name	2-Buten-1-One, 2,3-Difluoro-1-Phenyl-, (2Z)- (9Ci)
CAS No.	366799-75-9
Molecular Formula	C10H6F2O
Molecular Weight	180.15 g/mol
Synonyms	(2Z)-2,3-Difluoro-1-phenyl-2-buten-1-one; (Z)-2,3-Difluoro-1-phenylbut-2-en-1-one; 2-Buten-1-one, 2,3-difluoro-1-phenyl-, (Z)-; 366799-75-9; (Z)-2,3-Difluorochalcone; 1-Phenyl-2,3-difluorobut-2-en-1-one (Z-isomer)
EINECS	Contact for details

Quality Control

Every batch of 2-Buten-1-One, 2,3-Difluoro-1-Phenyl-, (2Z)- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) including results from HPLC, GC, NMR, and other relevant analyses is supplied with each shipment to guarantee it meets your specified requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases, reducing agents, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.