Description

2-Buten-1-One, 2,3-Difluoro-1-Phenyl-, (2E)- (9Ci) is a high-purity, fluorinated α,β-unsaturated ketone building block. This compound matters for its role as a versatile synthon in advanced organic synthesis, enabling the introduction of difluoroalkene and phenyl ketone motifs into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those requiring fluorinated scaffolds to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the difluoroalkene group can enhance biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with unique optical or electronic properties.
• Organic Synthesis Reagent: Employed in Michael additions, cycloadditions, and other C-C bond-forming reactions to construct complex molecular architectures in academic and industrial laboratories.
• Fluorine Chemistry Studies: Acts as a model compound for investigating the reactivity and stereochemistry of gem-difluoro olefins in synthetic methodology development.

Basic Information

Product Name	2-Buten-1-One, 2,3-Difluoro-1-Phenyl-, (2E)- (9Ci)
CAS No.	366799-74-8
Molecular Formula	C10H6F2O
Molecular Weight	180.15 g/mol
Synonyms	(2E)-2,3-Difluoro-1-phenyl-2-buten-1-one; 2,3-Difluoro-1-phenyl-2-buten-1-one, (E)-; 1-Phenyl-2,3-difluorobut-2-en-1-one; (E)-2,3-Difluoro-1-phenylbut-2-en-1-one; 366799-74-8; (E)-2,3-Difluoro-1-phenyl-2-buten-1-one; 2-Buten-1-one, 2,3-difluoro-1-phenyl-, (2E)-
EINECS	Contact for details

Quality Control

Our 2-Buten-1-One, 2,3-Difluoro-1-Phenyl-, (2E)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.