Description

Bicyclo[2.2.1]Heptane-2-Acetonitrile, 2-Hydroxy-1,3,3-Trimethyl-, (1R,2R,4S)- (9Ci) is a high-purity, chiral bicyclic nitrile derivative that serves as a sophisticated building block in advanced organic synthesis. Its rigid, functionalized structure is critical for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for creating novel active pharmaceutical ingredients (APIs) and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, especially in central nervous system (CNS) and antiviral research.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel ligands for transition metal catalysts in enantioselective synthesis.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and fragrances requiring specific stereocenters.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and exploring new reaction pathways.
• Material Science Research: Potential monomer or cross-linking agent for creating polymers with unique thermal or mechanical properties.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Acetonitrile, 2-Hydroxy-1,3,3-Trimethyl-, (1R,2R,4S)- (9Ci)
CAS No.	366013-96-9
Molecular Formula	C12H19NO
Molecular Weight	193.29 g/mol
Synonyms	(1R,2R,4S)-2-Hydroxy-1,3,3-trimethylbicyclo[2.2.1]heptane-2-acetonitrile; (1R,2R,4S)-2-Hydroxy-1,3,3-trimethyl-2-norbornaneacetonitrile; 2-Norbornaneacetonitrile, 2-hydroxy-1,3,3-trimethyl-, (1R-endo)-; endo-(1R,2R,4S)-2-Hydroxy-1,3,3-trimethylbicyclo[2.2.1]heptane-2-acetonitrile; Chiral Hydroxy Nitrile Camphor Derivative
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Acetonitrile, 2-Hydroxy-1,3,3-Trimethyl-, (1R,2R,4S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.