Description

Bicyclo[2.2.1]Heptane-2-Acetonitrile, 2-Hydroxy-1,7,7-Trimethyl-, (1R,2S,4R)- (9Ci) is a high-purity, stereochemically defined chiral building block derived from camphor. This compound matters as a versatile synthon for introducing complex, rigid bicyclic frameworks into target molecules, which is critical for modulating the physical and biological properties of advanced materials and pharmaceuticals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used to construct advanced, bioactive molecules for crop protection agents, leveraging its rigid, hydrophobic structure.
• Asymmetric Catalysis Ligand Precursor: Provides a scaffold for developing novel chiral ligands and organocatalysts.
• Fragrance & Flavor Chemistry: Acts as an intermediate for synthesizing high-value aroma chemicals with unique olfactory profiles.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals where a rigid, chiral core is required.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and stereochemistry.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Acetonitrile, 2-Hydroxy-1,7,7-Trimethyl-, (1R,2S,4R)- (9Ci)
CAS No.	366013-95-8
Molecular Formula	C₁₂H₁₉NO
Molecular Weight	193.28 g/mol
Synonyms	(1R,2S,4R)-2-Hydroxy-1,7,7-trimethylbicyclo[2.2.1]heptane-2-acetonitrile; (-)-Camphor-2-acetonitrile; 2-(2-Hydroxy-1,7,7-trimethylbicyclo[2.2.1]hept-2-yl)acetonitrile; (1R,2S,4R)-2-Hydroxy-1,7,7-trimethylnorbornane-2-acetonitrile; Camphor-derived acetonitrile; L-Camphor acetonitrile derivative; Bicyclo[2.2.1]heptane-2-acetonitrile, 2-hydroxy-1,7,7-trimethyl-, (1R-endo)-
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Acetonitrile, 2-Hydroxy-1,7,7-Trimethyl-, (1R,2S,4R)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.