Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxamide, 3-Amino-, (1R,2S,3R,4S)- (9Ci) is a high-purity, stereochemically defined chiral building block with the CAS number 365544-39-4. This compound is valued for its rigid norbornene-based scaffold and functional handles, making it a critical intermediate in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecules, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-viral therapies.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its structural rigidity for enhanced biological activity.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for synthesizing chiral ligands and organocatalysts.
• Material Science Monomer: Potential use in creating specialized polymers with unique thermal and mechanical properties via ring-opening metathesis polymerization (ROMP).
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploring new chemical spaces.
• Fine Chemical Synthesis: A versatile building block for producing other high-value, stereochemically complex fine chemicals and flavors/fragrances intermediates.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxamide, 3-Amino-, (1R,2S,3R,4S)- (9Ci)
CAS No.	365544-39-4
Molecular Formula	C8H12N2O
Molecular Weight	152.19 g/mol
Synonyms	(1R,2S,3R,4S)-3-Aminobicyclo[2.2.1]hept-5-ene-2-carboxamide; endo-3-Amino-2-norbornenecarboxamide; 3-Amino-2-norbornene-2-carboxamide; 3-Aminobicyclo[2.2.1]hept-5-ene-2-carboxylic acid amide; (1R,2S,3R,4S)-3-Amino-2-norbornene-5-carboxamide; Bicyclo[2.2.1]hept-5-ene-2-carboxamide, 3-amino-, (1R-endo)-; 365544-39-4
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Carboxamide, 3-Amino-, (1R,2S,3R,4S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.