Description

2,4-Cyclohexadiene-1-Acetonitrile, 1,6-Dihydroxy-, (1R,6S)-Rel- (9Ci) is a specialized chiral dihydroxy nitrile derivative, a high-value intermediate in advanced organic synthesis. This compound matters for its precise stereochemistry and functional group array, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its dihydroxy and nitrile functionalities.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new asymmetric catalytic reactions.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fragrances, flavors, and other high-value specialty chemicals.
• Academic & Institutional Research: A tool compound for studying cycloaddition reactions, nucleophilic addition to conjugated systems, and stereoselective transformations.
• Material Science Precursor: Potential starting material for the synthesis of functionalized polymers or organic electronic materials.

Basic Information

Product Name	2,4-Cyclohexadiene-1-Acetonitrile, 1,6-Dihydroxy-, (1R,6S)-Rel- (9Ci)
CAS No.	365458-95-3
Molecular Formula	C8H9NO2
Molecular Weight	151.16 g/mol
Synonyms	(1R,6S)-rel-1,6-Dihydroxy-2,4-cyclohexadiene-1-acetonitrile; 1,6-Dihydroxy-2,4-cyclohexadiene-1-acetonitrile, (1R,6S)-rel-; 2,4-Cyclohexadiene-1-acetonitrile, 1,6-dihydroxy-, (1R,6S)-rel-; rel-(1R,6S)-1,6-Dihydroxy-2,4-cyclohexadiene-1-acetonitrile; 365458-95-3; (1R,6S)-1,6-Dihydroxy-1-(cyanomethyl)-1,3-cyclohexadiene
EINECS	Contact for details

Quality Control

Our 2,4-Cyclohexadiene-1-Acetonitrile, 1,6-Dihydroxy-, (1R,6S)-Rel- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure consistent identity, purity, and stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP-compliant development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be light-sensitive and/or hygroscopic; handle and store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.