Description

3,3,3-Trifluoropropanethioamide is a specialized fluorinated thioamide building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a thioamide group and a trifluoromethyl moiety, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine atoms.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Employed in the synthesis of monomers and polymers with specific optical or electronic properties for advanced materials.
• Fluorine Chemistry: An essential reagent for introducing the CF3 group and thioamide functionality into complex molecular architectures in medicinal and synthetic chemistry.

Basic Information

Product Name	3,3,3-Trifluoropropanethioamide
CAS No.	365428-34-8
Molecular Formula	C3H4F3NS
Molecular Weight	143.13 g/mol
Synonyms	3,3,3-Trifluoropropanethioamide; 3,3,3-Trifluoropropionthioamide; 3,3,3-Trifluoropropionic acid thioamide; Propanethioamide, 3,3,3-trifluoro-; 3,3,3-Trifluoropropane-1-thioamide; Trifluoropropionthioamide
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoropropanethioamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.