Description

4-Nitro-n-(2,2,2-Trifluoroethyl)Benzamide is a specialized fluorinated benzamide derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a nitro and a trifluoroethyl group, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the nitro and trifluoroethyl groups can contribute to specific biological activity and environmental persistence profiles.
• Material Science: Acts as a monomer or functionalizing agent in the production of specialty polymers and liquid crystals, imparting unique electronic and surface properties.
• Chemical Synthesis: Serves as a versatile reagent for introducing the N-(2,2,2-trifluoroethyl)benzamide scaffold into more complex molecular architectures in academic and industrial research settings.
• Fluorine Chemistry: A valuable compound for studying structure-activity relationships (SAR) in fluorinated organic molecules, aiding in the design of compounds with optimized physical and chemical characteristics.

Basic Information

Product Name	4-Nitro-n-(2,2,2-Trifluoroethyl)Benzamide
CAS No.	365425-94-1
Molecular Formula	C9H7F3N2O3
Molecular Weight	248.16 g/mol
Synonyms	4-Nitro-N-(2,2,2-trifluoroethyl)benzamide; N-(2,2,2-Trifluoroethyl)-4-nitrobenzamide; Benzamide, 4-nitro-N-(2,2,2-trifluoroethyl)-; 4-Nitrobenzoic acid (2,2,2-trifluoroethyl)amide; p-Nitro-N-(2,2,2-trifluoroethyl)benzamide; 365425-94-1; N-(Trifluoroethyl)-4-nitrobenzamide
EINECS	Contact for details

Quality Control

Our 4-Nitro-n-(2,2,2-Trifluoroethyl)Benzamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.