Description

4'-(Trifluoromethyl)-4-Biphenylboronic Acid is a high-purity organoboron compound, a key building block in modern synthetic chemistry. Its value lies in enabling precise cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex biaryl structures. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing trifluoromethylated biaryl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the biphenyl scaffold imparts specific biological activity.
• Material Science: Serves as a monomer or precursor in the creation of organic electronic materials, including OLEDs, semiconductors, and liquid crystals.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds efficiently and with high selectivity.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating complex molecular architectures.
• Ligand Synthesis: Can be utilized to prepare specialized ligands for catalysis and coordination chemistry.

Basic Information

Product Name	4'-(Trifluoromethyl)-4-Biphenylboronic Acid
CAS No.	364590-93-2
Molecular Formula	C₁₃H₁₀BF₃O₂
Molecular Weight	266.03 g/mol
Synonyms	[4-(Trifluoromethyl)phenyl]boronic Acid; 4'-(Trifluoromethyl)biphenyl-4-boronic Acid; 4-(4-(Trifluoromethyl)phenyl)phenylboronic Acid; 4-Biphenylboronic Acid, 4'-(trifluoromethyl)-; p-(Trifluoromethyl)biphenyl-4-boronic Acid; (4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-yl)boronic Acid
EINECS	Contact for details

Quality Control

Every batch of 4'-(Trifluoromethyl)-4-Biphenylboronic Acid is manufactured and tested under strict quality management protocols to ensure consistency and reliability. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.