Description

tert-Butyl 2-Hydroxyethyl(2-(2,2,2-Trifluoroacetamido)Ethyl)Carbamate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex bioactive molecules. This compound is critical for research and development in medicinal chemistry, particularly in constructing sophisticated peptide mimetics and targeted drug conjugates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring reliable, high-quality building blocks for next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), especially for oncology and neurological disorders.
• Peptidomimetic Synthesis: Used to introduce protected amino acid-like structures with trifluoroacetamide and carbamate functionalities into peptide chains.
• Protease Inhibitor Development: Serves as a precursor in creating inhibitors that target specific enzymatic pathways.
• Linker Chemistry for Drug Conjugates: Employed in the development of Antibody-Drug Conjugates (ADCs) and other targeted delivery systems due to its reactive hydroxyl and protected amine groups.
• Chemical Biology Research: Utilized as a tool compound for studying protein-protein interactions and enzyme mechanisms.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	tert-Butyl 2-Hydroxyethyl(2-(2,2,2-Trifluoroacetamido)Ethyl)Carbamate
CAS No.	364056-55-3
Molecular Formula	C11H19F3N2O4
Molecular Weight	300.28 g/mol
Synonyms	Boc-NH-CH2CH2-N(TFA)-CH2CH2-OH; 2-[[(2,2,2-Trifluoroacetyl)amino]ethyl](2-hydroxyethyl)carbamic acid tert-butyl ester; 1,1-Dimethylethyl N-[2-[[(2,2,2-trifluoroacetyl)amino]ethyl]-2-hydroxyethyl]carbamate; N-(tert-Butoxycarbonyl)-N-(2-hydroxyethyl)-N'-(2,2,2-trifluoroacetyl)ethylenediamine; tert-Butyl [2-hydroxy-2-[(2,2,2-trifluoroacetamido)ethyl]amino]ethylcarbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Hydroxyethyl(2-(2,2,2-Trifluoroacetamido)Ethyl)Carbamate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.