Description

2,2,2-Trifluoro-n-(2-(2-Hydroxyethylamino)Ethyl)Acetamide is a specialized fluorinated acetamide derivative, valued for its unique trifluoromethyl group and bifunctional amino-alcohol structure. This compound serves as a critical building block in advanced organic synthesis, enabling the introduction of fluorine atoms and reactive handles into target molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, as well as by fine chemical manufacturers producing high-value intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting protease inhibitors or molecules requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can significantly improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis or for modifying metal complexes used in cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers, surface modifiers, or specialty coatings that require specific solubility and surface energy properties.
• Bioconjugation and Probe Synthesis: The reactive amine and hydroxyl groups make it suitable for constructing fluorescent probes, affinity tags, or linkers in bioconjugation chemistry.

Basic Information

Item	Details
Product Name	2,2,2-Trifluoro-n-(2-(2-Hydroxyethylamino)Ethyl)Acetamide
CAS No.	364056-54-2
Molecular Formula	C8H13F3N2O2
Molecular Weight	226.20 g/mol
Synonyms	N-[2-(2-Hydroxyethylamino)ethyl]-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[2-[(2-hydroxyethyl)amino]ethyl]acetamide; 2,2,2-Trifluoroacetamide, N-[2-[(2-hydroxyethyl)amino]ethyl]-; N-(2-((2-Hydroxyethyl)amino)ethyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(2-(2-hydroxyethylamino)ethyl)acetamide; TFA-HAEE; Trifluoroacetamide hydroxyethylaminoethyl derivative
EINECS	Contact for details

Quality Control

Our production of 2,2,2-Trifluoro-n-(2-(2-Hydroxyethylamino)Ethyl)Acetamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) documenting identity, purity, and specific tests is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.