Description

n-(3-Chloromethyl-Phenyl)-Methanesulfonamide is a specialized aromatic sulfonamide derivative featuring a reactive chloromethyl group. This compound is a valuable chemical intermediate, prized for its ability to introduce both sulfonamide and benzyl chloride functionalities into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for creating sulfonamide-based pharmacophores with modified activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the chloromethyl-phenyl moiety is required.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Chemical Biology Probes: Utilized in the design of molecular probes and affinity labels due to its reactive chloromethyl group for covalent binding studies.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the N-(phenylmethanesulfonamide) group into more complex organic structures.

Basic Information

Product Name	n-(3-Chloromethyl-Phenyl)-Methanesulfonamide
CAS No.	362529-31-5
Molecular Formula	C8H10ClNO2S
Molecular Weight	219.69 g/mol
Synonyms	N-[(3-Chloromethyl)phenyl]methanesulfonamide; 3-[(Methylsulfonyl)amino]benzyl chloride; 1-(Chloromethyl)-3-[(methylsulfonyl)amino]benzene; Methanesulfonamide, N-[3-(chloromethyl)phenyl]-; N-(3-Chlorobenzyl)methanesulfonamide; Benzenemethanesulfonamide, α-chloro-3-amino- (related); α-Chloro-m-toluenesulfonamide (related form)
EINECS	Contact for details

Quality Control

Every batch of n-(3-Chloromethyl-Phenyl)-Methanesulfonamide is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed results from HPLC, NMR, and other spectroscopic methods to verify identity, purity, and conformity to agreed specifications. Our commitment ensures material consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.