Description

(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-Bis(Diphenylphosphino)-3,3'-Bipyridine is a high-value, chiral bidentate phosphine ligand crucial for asymmetric catalysis. Its core value proposition lies in enabling highly enantioselective transformations, which are essential for the efficient and cost-effective synthesis of single-enantiomer pharmaceutical intermediates and fine chemicals. This product is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who are developing novel synthetic routes requiring precise stereochemical control.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for the synthesis of enantiomerically pure amino acids, amines, and alcohols.
• As a key component in asymmetric cross-coupling reactions (e.g., Suzuki-Miyaura, Heck) to construct chiral biaryl and other complex molecular architectures.
• For the development of novel catalytic systems in academic and industrial research focused on green chemistry and atom economy.
• In the synthesis of advanced pharmaceutical intermediates where high enantiomeric excess (ee) is a critical quality attribute.
• As a precursor or modifier for immobilized catalysts used in continuous flow chemistry applications.
• For the preparation of chiral metal complexes used in material science and organic electronics.

Basic Information

Product Name	(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-Bis(Diphenylphosphino)-3,3'-Bipyridine
CAS No.	362524-23-0
Molecular Formula	C42H38N2O4P2
Molecular Weight	696.71 g/mol
Synonyms	(R)-(+)-DTBM-SEGPHOS; (R)-DTBM-SEGPHOS; (R)-5,5'-Bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole; (R)-2,2',6,6'-Tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine; (R)-DTBM-Segphos; (R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridyl; (R)-DTBM-SEGPHOS ligand; (R)-DTBM-SegPhos
EINECS	Contact for details

Quality Control

Our (R)-(+)-DTBM-SEGPHOS is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive catalytic applications. Each lot undergoes comprehensive analytical characterization, including chiral purity assessment by HPLC. A Certificate of Analysis (COA) detailing specific results for identity, assay, and enantiomeric excess is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to minimize oxidation and ensure long-term stability. The product is sensitive to air and moisture; handle and store in a controlled environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.