Description

3-Furancarboxylicacid,4-Aminotetrahydro-,Methylester,(3R,4S)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting the central nervous system. Pharmaceutical research and development organizations, as well as fine chemical manufacturers, need this precise chemical to create enantiomerically pure active pharmaceutical ingredients (APIs) and complex natural product analogs.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel drug candidates, particularly in neurological and psychiatric therapeutic areas.
• Asymmetric Synthesis: Used as a starting material or building block in catalytic asymmetric reactions to construct complex molecular architectures.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies and the exploration of new chemical space for bioactive compounds.
• Process Chemistry Development: Serves as a reference standard or key intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Agrochemical Research: Potential intermediate for developing new, enantiomerically pure crop protection agents with improved efficacy and environmental profiles.

Basic Information

Product Name	3-Furancarboxylicacid,4-Aminotetrahydro-,Methylester,(3R,4S)-(9Ci)
CAS No.	362488-80-0
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	(3R,4S)-4-Aminotetrahydrofuran-3-carboxylic acid methyl ester; Methyl (3R,4S)-4-aminotetrahydrofuran-3-carboxylate; 4-Aminotetrahydrofuran-3-carboxylic Acid Methyl Ester (3R,4S)-; Tetrahydro-4-amino-3-furancarboxylic Acid Methyl Ester, (3R,4S)-; (3R,4S)-Methyl 4-aminotetrahydrofuran-3-carboxylate; 362488-80-0; (3R,4S)-rel-4-Aminotetrahydro-3-furancarboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high enantiomeric purity. Each lot is fully characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.