Description

5Alpha-Androstan-3Alpha-Ol-17-One-16,16-D2-Glucosiduronate is a high-purity, deuterium-labeled glucuronide conjugate of a key steroid metabolite, specifically designed for advanced analytical and research applications. This compound is essential for use as an internal standard in mass spectrometry, enabling precise quantification and method validation in complex biological matrices. It is primarily utilized by analytical laboratories, clinical research organizations, and pharmaceutical developers working in endocrinology, anti-doping control, and metabolic disorder studies.

Application

• Internal Standard for LC-MS/MS: Critical for the accurate quantification of steroid metabolites in urine, serum, and plasma for clinical diagnostics and research.
• Doping Control Analysis: Used in anti-doping laboratories to detect and confirm the presence of endogenous anabolic steroids and their metabolites.
• Endocrine Research: Supports studies on androgen metabolism, steroidogenesis pathways, and related disorders.
• Pharmaceutical Development: Aids in the pharmacokinetic and metabolic profiling of new drug candidates targeting hormone pathways.
• Forensic Toxicology: Employed in confirmatory testing for anabolic steroid abuse in forensic investigations.
• Method Development & Validation: Serves as a stable, isotopically-labeled reference material to develop and validate robust analytical methods.

Basic Information

Product Name	5Alpha-Androstan-3Alpha-Ol-17-One-16,16-D2-Glucosiduronate
CAS No.	362049-52-3
Molecular Formula	C25H36D2O9
Molecular Weight	476.57 g/mol
Synonyms	5α-Androstan-3α-ol-17-one 16,16-d2 Glucuronide; Etiocholanolone-d2 Glucuronide; 3α-Hydroxy-5α-androstan-17-one 16,16-d2 Glucuronide; 5α-Androstane-3α,17β-diol-17-one 16,16-d2 Glucuronide; Etiocholanolone Glucuronide-d2; Androsterone Glucuronide-d2 (related metabolite); Deuterium Labeled Steroid Glucuronide; Internal Standard for Etiocholanolone Glucuronide
EINECS	Contact for details

Quality Control

Our 5Alpha-Androstan-3Alpha-Ol-17-One-16,16-D2-Glucosiduronate is manufactured under strict quality systems to ensure the highest standards of purity and isotopic enrichment required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, isotopic purity (D-enrichment), and absence of interfering impurities. We adhere to ISO 9001 quality management principles, and our products are suitable for use in regulated environments under GLP/GMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain integrity. Allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.