Description

tert-Butyl 4-Bromo-3,5-Dimethylphenylcarbamate is a high-purity, protected aniline derivative of significant importance in advanced organic synthesis. This compound serves as a critical building block for the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), fine chemicals, and novel material precursors.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those requiring a halogenated, protected aniline moiety for further functionalization.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the bromine atom and carbamate group offer sites for structural diversification.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers requiring specific aromatic building blocks.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 4-Bromo-3,5-Dimethylphenylcarbamate
CAS No.	361436-27-3
Molecular Formula	C13H18BrNO2
Molecular Weight	300.19 g/mol
Synonyms	4-Bromo-3,5-dimethylphenylcarbamic acid tert-butyl ester; tert-Butyl N-(4-bromo-3,5-dimethylphenyl)carbamate; Carbamic acid, N-(4-bromo-3,5-dimethylphenyl)-, 1,1-dimethylethyl ester; BOC-4-Bromo-3,5-dimethylaniline; 1-(tert-Butoxycarbonylamino)-4-bromo-3,5-dimethylbenzene; N-Boc-4-bromo-3,5-dimethylaniline
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Bromo-3,5-Dimethylphenylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.