Description

Methyl 2-(2,6-Difluoro-3-Nitrophenyl)Acetate is a high-purity, multi-functional aromatic ester building block critical for advanced organic synthesis. Its molecular structure, featuring both electron-withdrawing nitro and fluorine substituents, makes it an essential intermediate for constructing complex, biologically active molecules. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoro-nitrophenyl moiety contributes to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and electron-deficient character.
• Chemical Research & Development: A versatile synthon for medicinal chemistry and process chemistry, enabling Suzuki couplings, nucleophilic aromatic substitutions, and ester transformations.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized fluorinated dyes and colorants.

Basic Information

Product Name	Methyl 2-(2,6-Difluoro-3-Nitrophenyl)Acetate
CAS No.	361336-79-0
Molecular Formula	C9H7F2NO4
Molecular Weight	231.15 g/mol
Synonyms	Methyl (2,6-Difluoro-3-nitrophenyl)acetate; Acetic acid, 2-(2,6-difluoro-3-nitrophenyl)-, methyl ester; 2-(2,6-Difluoro-3-nitrophenyl)acetic acid methyl ester; Methyl 2,6-difluoro-3-nitrobenzeneacetate; 361336-79-0; Methyl α-(2,6-difluoro-3-nitrophenyl)acetate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(2,6-Difluoro-3-Nitrophenyl)Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.