Description

(+)-(S)-tert-Butylmethylphosphine-Borane is a high-purity, chiral organophosphorus compound supplied as a stable borane complex. This product is a critical chiral ligand precursor and catalyst component, valued for its ability to impart high enantioselectivity in asymmetric synthesis. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and advanced materials.

Application

• Asymmetric Catalysis: As a chiral ligand precursor for transition metal catalysts (e.g., Rh, Ru, Pd) in enantioselective hydrogenation, hydroformylation, and cross-coupling reactions.
• Pharmaceutical Intermediates: Synthesis of chiral active pharmaceutical ingredients (APIs) requiring high optical purity.
• Agrochemical Synthesis: Production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Key building block for specialty chemicals, flavors, and fragrances where stereochemistry is crucial.
• Academic & Industrial R&D: A versatile tool for methodological development in organic synthesis and catalysis research.
• Material Science: Potential precursor for chiral polymers or metal-organic frameworks (MOFs) with specific stereochemical properties.

Basic Information

Product Name	(+)-(S)-tert-Butylmethylphosphine-Borane
CAS No.	360787-11-7
Molecular Formula	C5H14BP
Molecular Weight	116.95 g/mol
Synonyms	(S)-tert-Butylmethylphosphine Borane Complex; (S)-t-BuMePH•BH3; (S)-tert-Butyl(methyl)phosphane-Borane; (S)-tert-Butylmethylphosphine-Borane Adduct; (S)-t-BuPH(CH3)•BH3; (S)-BMP-Borane; (S)-tert-Butylmethylphosphane-Trihydroboron
EINECS	Contact for details

Quality Control

Our (+)-(S)-tert-Butylmethylphosphine-Borane is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric excess. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and identity. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical development and commercial production.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, well-ventilated area. Keep away from heat, sparks, and open flame. Due to its sensitivity to oxidation, the container should be flushed with inert gas after each opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.