Description

2-Amino-N-(2,2,2-trifluoroethyl)acetamide is a specialized trifluoroethyl-substituted acetamide derivative, serving as a high-value building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a trifluoroethyl group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders or requiring metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with unique surface properties or fluorine-based functionalities.
• Chemical Biology Probes: Utilized to develop molecular probes and biochemical tools for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	2-Amino-N-(2,2,2-trifluoroethyl)acetamide
CAS No.	359821-38-8
Molecular Formula	C4H7F3N2O
Molecular Weight	156.11 g/mol
Synonyms	N-(2-Aminoacetyl)-2,2,2-trifluoroethanamine; Glycinamide, N-(2,2,2-trifluoroethyl)-; 2,2,2-Trifluoro-N-(2-aminoacetyl)ethanamine; 2-Aminoacetamide, N-(2,2,2-trifluoroethyl)-; Acetamide, 2-amino-N-(2,2,2-trifluoroethyl)-; 359821-38-8; TFEA; Trifluoroethylglycinamide
EINECS	Contact for details

Quality Control

Our 2-Amino-N-(2,2,2-trifluoroethyl)acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.