Description

n-(Methanethiosulfonylethylcarboxamidoethyl)-5-Naphthylamine-1-Sulfonic Acid, Sodium Salt is a specialized, high-purity organic intermediate featuring a reactive methanethiosulfonate group and a naphthylamine sulfonic acid moiety. This compound matters for its role as a critical building block in the synthesis of advanced materials and functional molecules, offering precise chemical reactivity for conjugation and derivatization. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors for developing novel drug candidates, diagnostic reagents, and high-performance polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted drug conjugates, particularly for antibody-drug conjugates (ADCs) and other biopharmaceuticals.
• Bioconjugation Reagent: Used for site-specific labeling and modification of proteins, peptides, and antibodies via its reactive thiol-reactive methanethiosulfonate group.
• Fluorescent Probe Synthesis: Serves as a core component for creating naphthalene-based fluorescent dyes and sensors used in bioimaging and diagnostic assays.
• Polymer Chemistry: Functional monomer for introducing sulfonate and aromatic groups into specialty polymers to modify solubility, adhesion, or optical properties.
• Research & Development: Essential tool compound in academic and industrial R&D for exploring new chemical entities and reaction pathways in organic synthesis.
• Diagnostic Reagent Manufacturing: Used in the production of chemical components for clinical diagnostic kits and assays.

Basic Information

Product Name	n-(Methanethiosulfonylethylcarboxamidoethyl)-5-Naphthylamine-1-Sulfonic Acid, Sodium Salt
CAS No.	359436-83-2
Molecular Formula	C₁₆H₁₉N₂NaO₅S₃
Molecular Weight	438.51 g/mol
Synonyms	5-[[2-[[(2-Sulfonatoethyl)amino]carbonyl]ethyl]dithio]-1-naphthalenesulfonic acid sodium salt; Sodium 5-[(2-{[(2-sulfonatoethyl)carbamoyl]ethyl}disulfanyl)naphthalene-1-sulfonate; MTSEA-Naphthylamine Sulfonate Sodium Salt; (2-{[(2-Sulfonatoethyl)carbamoyl]ethyl}disulfanyl)naphthalene-1-sulfonic acid sodium salt; 1,5-Naphthalenedisulfonic acid derivative, sodium salt; Thiol-reactive naphthylamine sulfonate; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our n-(Methanethiosulfonylethylcarboxamidoethyl)-5-Naphthylamine-1-Sulfonic Acid, Sodium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for research and pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange-brown powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.