Description

1-Naphthalenol,2-Fluoro-1,2-Dihydro-,(1R,2R)-(9Ci) is a chiral, fluorinated naphthalene derivative of significant interest in advanced organic synthesis. This compound matters as a high-value building block for creating complex molecules with precise stereochemistry, which is critical for developing pharmaceuticals and agrochemicals with targeted activity. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring fluorinated, stereochemically defined structures.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom and specific stereochemistry can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric catalytic reactions.
• Material Science Research: Investigated as a monomer or functional additive for creating specialty polymers with unique optical or electronic properties.
• Academic and R&D Laboratories: Employed in fundamental research exploring new fluorination methodologies, reaction mechanisms, and the synthesis of complex natural product analogs.

Basic Information

Product Name	1-Naphthalenol,2-Fluoro-1,2-Dihydro-,(1R,2R)-(9Ci)
CAS No.	357625-18-4
Molecular Formula	C₁₀H₉FO
Molecular Weight	164.18 g/mol
Synonyms	(1R,2R)-2-Fluoro-1,2-dihydro-1-naphthol; (1R,2R)-2-Fluoro-1,2-dihydronaphthalen-1-ol; 2-Fluoro-(1R,2R)-1,2-dihydro-1-naphthol; (1R,2R)-1-Naphthalenol, 2-fluoro-1,2-dihydro-; Fluorinated Dihydronaphthol; Chiral Fluoronaphthol; (1R,2R)-Enantiomer of 2-Fluoro-1,2-dihydronaphthalen-1-ol
EINECS	Contact for details

Quality Control

Our 1-Naphthalenol,2-Fluoro-1,2-Dihydro-,(1R,2R)-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC/MS to confirm identity, enantiomeric excess, and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to light.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.