Description

5-Bromo-n-(tert-Butyl)-2-Furamide is a specialized brominated furan derivative, a high-value intermediate in advanced organic synthesis. Its unique structure, featuring both a bromine substituent and a sterically hindered tert-butyl amide group, makes it a critical building block for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, leveraging the furan ring's bioactivity.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe Development: Utilized to create labeled compounds or molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig couplings.
• Ligand and Catalyst Preparation: Employed in the synthesis of novel nitrogen-containing ligands for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Bromo-n-(tert-Butyl)-2-Furamide
CAS No.	356562-19-1
Molecular Formula	C9H12BrNO2
Molecular Weight	246.10 g/mol
Synonyms	5-Bromo-N-tert-butylfuran-2-carboxamide; 5-Bromo-2-furancarboxamide, N-(1,1-dimethylethyl)-; N-(tert-Butyl)-5-bromofuran-2-carboxamide; 5-Bromo-N-(tert-butyl)furan-2-carboxamide; 2-Furancarboxamide, 5-bromo-N-(1,1-dimethylethyl)-; 5-Bromo-N-(tert-butyl)-2-furamide; tert-Butyl 5-bromofuran-2-carboxamide
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-(tert-Butyl)-2-Furamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.