Description

Ac-Met-Amc CAS NO 354152-20-8 is a specialized protected amino acid derivative, specifically an acetylated methionine amide. This compound is a crucial building block in advanced peptide synthesis and pharmaceutical research, offering precise control over molecular structure and reactivity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic peptides and conducting biochemical studies.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of methionine residues into peptide chains, preventing unwanted side reactions.
• Pharmaceutical Intermediate: Serves as a critical precursor in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in enzymatic studies, protein modeling, and as a standard in analytical method development for amino acid analysis.
• Protecting Group Strategy: The acetyl (Ac) and amide (Amc) groups protect reactive functionalities, enabling complex multi-step synthetic sequences.
• Combinatorial Chemistry: Employed in libraries for drug discovery to create diverse arrays of methionine-containing compounds.

Basic Information

Product Name	Ac-Met-Amc
CAS No.	354152-20-8
Molecular Formula	C9H16N2O3S
Molecular Weight	232.30 g/mol
Synonyms	N-Acetyl-L-methioninamide; Acetyl-Methionine Amide; Ac-Met-NH2; N-Acetyl-L-methionine amide; L-Methionine, N-acetyl-, amide; N-Acetylmethioninamide; Ac-Met-Amc; Nα-Acetyl-L-methioninamide
EINECS	Contact for details

Quality Control

Our Ac-Met-Amc is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric purity, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.