Description

(R)-(-)-2,2'-Bis[Di(3,5-Di-I-Propyl-4-Dimethylaminophenyl)Phosphino]-6,6'-Dimethoxy-1,1'-Biphenyl,Min.97% is a high-purity, chiral bisphosphine ligand of significant importance in asymmetric catalysis. Its value lies in its ability to induce high enantioselectivity in transition metal-catalyzed reactions, which is critical for the efficient synthesis of single-enantiomer compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-performance ligands for creating chiral intermediates and active ingredients.

Application

• As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical intermediate synthesis.
• Enabling enantioselective C-C bond formation (e.g., cross-coupling, allylic substitution) in advanced organic synthesis.
• Catalyst development for the production of optically pure agrochemicals and flavors/fragrances.
• Use in academic and industrial R&D to explore new catalytic methodologies.
• Potential application in the synthesis of chiral ligands and catalysts with tailored properties.

Basic Information

Product Name	(R)-(-)-2,2'-Bis[Di(3,5-Di-I-Propyl-4-Dimethylaminophenyl)Phosphino]-6,6'-Dimethoxy-1,1'-Biphenyl, Min. 97%
CAS No.	352655-40-4
Molecular Formula	C78H108I4N4O2P2
Molecular Weight	1684.31 g/mol
Synonyms	(R)-DTBM-SEGPHOS; (R)-(-)-DTBM-SEGPHOS; (R)-3,5-di-tert-Butyl-4-methoxyphenyl-SEGPHOS; (R)-DTBM-Segphos; (R)-Bis[di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-2,2'-dimethoxy-1,1'-biphenyl; (R)-(-)-2,2'-Bis(di(3,5-di-tert-butyl-4-methoxyphenyl)phosphino)-6,6'-dimethoxy-1,1'-biphenyl; (R)-DTBM-SegPhos ligand
EINECS	Contact for details

Quality Control

Our (R)-DTBM-SEGPHOS is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes comprehensive analysis, including chiral purity verification and metal residue screening. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain catalytic activity and purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow powder or crystals
Identification (IR)	Conforms to structure
Assay (HPLC)	Min. 97.0%
Chiral Purity (HPLC)	Min. 99.0% ee
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.