Description

(3-Chloro-2-Fluoro-5-Methylphenyl)Boronic Acid is a high-purity, synthetically valuable organoboron building block essential for modern cross-coupling reactions. Its primary commercial value lies in enabling the efficient and precise construction of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in modern herbicides, fungicides, and insecticides, contributing to improved crop protection.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and organic photovoltaics.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other advanced catalytic processes.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) agents for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke organic compounds for client projects.

Basic Information

Product Name	(3-Chloro-2-Fluoro-5-Methylphenyl)Boronic Acid
CAS No.	352535-88-7
Molecular Formula	C7H7BClFO2
Molecular Weight	187.39 g/mol
Synonyms	2-Fluoro-3-chloro-5-methylbenzeneboronic acid; (3-Chloro-2-fluoro-5-methylphenyl)boronic acid; 3-Chloro-2-fluoro-5-methylbenzeneboronic acid; Boronic acid, B-(3-chloro-2-fluoro-5-methylphenyl)-; 352535-88-7; 3-Chloro-2-fluoro-5-methylphenylboronic acid; (2-Fluoro-3-chloro-5-methylphenyl)boronic acid
EINECS	Contact for details

Quality Control

Our (3-Chloro-2-Fluoro-5-Methylphenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive cross-coupling chemistry. Certificates of Analysis (COA) with detailed chromatographic data are available upon request, providing full traceability and batch-specific quality assurance for your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.