Description

3-Bromo-2,6-Difluorophenylboronic Acid is a high-value organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through versatile cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a building block for synthesizing specialized ligands and catalysts used in asymmetric synthesis and polymerization processes.
• Material Science Research: Employed in the development of organic electronic materials, including OLEDs and semiconductors, due to its halogenated aromatic structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs serving the life sciences sector.

Basic Information

Product Name	3-Bromo-2,6-Difluorophenylboronic Acid
CAS No.	352535-84-3
Molecular Formula	C6H4BBrF2O2
Molecular Weight	236.81 g/mol
Synonyms	(3-Bromo-2,6-difluorophenyl)boronic Acid; 2,6-Difluoro-3-bromobenzeneboronic Acid; 3-Bromo-2,6-difluorobenzeneboronic Acid; Boronic acid, B-(3-bromo-2,6-difluorophenyl)-; 352535-84-3; 3-Br-2,6-F2PhB(OH)2; 3-Bromo-2,6-difluoro phenyl boronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2,6-Difluorophenylboronic Acid is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality commitment aligns with the standards demanded by cGMP and ISO 9001 environments for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.