Description

5-Chloro-2-Fluorophenylboronic Acid is a versatile and high-purity organoboron compound, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, facilitating the development of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl structures.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create boronic acid-based probes and sensors for detecting sugars and other biological analytes.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and academic laboratories exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	5-Chloro-2-Fluorophenylboronic Acid
CAS No.	352535-83-2
Molecular Formula	C6H5BClFO2
Molecular Weight	173.37 g/mol
Synonyms	(5-Chloro-2-fluorophenyl)boronic acid; 2-Fluoro-5-chlorophenylboronic acid; 5-Chloro-2-fluorobenzeneboronic acid; Boronic acid, B-(5-chloro-2-fluorophenyl)-; 352535-83-2; 5-Chloro-2-fluoro-benzeneboronic acid; (2-Fluoro-5-chlorophenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.