Description

4-Bromo-2,6-Difluorophenylboronic Acid is a high-purity organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This boronic acid is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing difluorophenyl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific halogenated aryl structures.
• Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as OLEDs and semiconductors.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.
• Custom Synthesis: Provides a foundational structure for contract research and manufacturing organizations (CROs/CMOs) to build bespoke molecules for clients.

Basic Information

Product Name	4-Bromo-2,6-Difluorophenylboronic Acid
CAS No.	352535-81-0
Molecular Formula	C6H4BBrF2O2
Molecular Weight	236.81 g/mol
Synonyms	(4-Bromo-2,6-difluorophenyl)boronic acid; 2,6-Difluoro-4-bromophenylboronic acid; 4-Bromo-2,6-difluorobenzeneboronic acid; B-(4-Bromo-2,6-difluorophenyl)boronic acid; 352535-81-0; 4-Br-2,6-F2-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,6-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.