Description

(S)-(-)n-Carbomethoxy-Alpha,α-Diphenyl -2-Pyrrolidinemethanol, 98% is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound matters for its role as a key building block in the production of active pharmaceutical ingredients (APIs) and other fine chemicals requiring precise stereochemistry. Pharmaceutical R&D laboratories and fine chemical manufacturers need it to develop and produce enantiomerically pure therapeutics, leveraging its defined stereocenter to control the biological activity of the final molecule.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs).
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for transition metal catalysis.
• Organic Synthesis Research: Serves as a versatile starting material in academic and industrial research for constructing complex molecules with defined stereochemistry.
• Agrochemical Synthesis: Employed in the development of chiral pesticides and herbicides where specific stereoisomers exhibit enhanced activity.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.

Basic Information

Product Name	(S)-(-)n-Carbomethoxy-Alpha,α-Diphenyl -2-Pyrrolidinemethanol, 98%
CAS No.	352535-68-3
Molecular Formula	C20H23NO3
Molecular Weight	325.40 g/mol
Synonyms	(S)-(-)-α,α-Diphenyl-2-pyrrolidinemethanol methyl carbamate; (S)-(-)-3-(Methoxycarbonylamino)-3,3-diphenyl-1-propanol; (S)-N-Carbomethoxy-α,α-diphenyl-2-pyrrolidinemethanol; (S)-Methyl (3-hydroxy-3,3-diphenylpropyl)carbamate; (S)-3-[(Methoxycarbonyl)amino]-3,3-diphenyl-1-propanol; (S)-α,α-Diphenyl-2-pyrrolidinemethanol N-carbamate methyl ester; A key intermediate for (S)-Duloxetine; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (S)-(-)n-Carbomethoxy-Alpha,α-Diphenyl -2-Pyrrolidinemethanol, 98% is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the specified 98% minimum assay and high enantiomeric excess. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.