Description

(R)-(+)-n-Carbomethoxy-2-Amino-1,1,2-Triphenylethanol is a high-value, chiral amino alcohol derivative that serves as a critical intermediate in asymmetric synthesis. Its importance lies in its role as a versatile building block and potential ligand for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and catalysts.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiopure drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand: Used in the development and preparation of chiral ligands for transition metal-catalyzed reactions, such as hydrogenation and C-C bond formation.
• Agrochemical Synthesis: Intermediate for creating chiral active ingredients in herbicides, fungicides, and plant growth regulators.
• Academic & Process Research: Valuable reagent for methodological studies in organic chemistry and scale-up process development for chiral molecules.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high enantiomeric purity for advanced materials and electronics.

Basic Information

Product Name	(R)-(+)-n-Carbomethoxy-2-Amino-1,1,2-Triphenylethanol
CAS No.	352535-67-2
Molecular Formula	C23H23NO3
Molecular Weight	361.44 g/mol
Synonyms	(R)-(+)-Methyl 2-Amino-3,3,3-triphenyl-2-hydroxypropanoate; (R)-Methyl 2-Amino-3,3,3-triphenyl-2-hydroxypropionate; (R)-2-Amino-3,3,3-triphenyl-2-hydroxypropionic Acid Methyl Ester; (R)-ATPE Methyl Ester; (1R)-2-Amino-1-hydroxy-1,1,2-triphenylethyl Carbamate (related); Carbomethoxy-ATPE; (R)-N-Carbomethoxy-2-amino-1,1,2-triphenylethanol
EINECS	Contact for details

Quality Control

Our (R)-(+)-n-Carbomethoxy-2-Amino-1,1,2-Triphenylethanol is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We employ advanced analytical techniques, including chiral HPLC and NMR, to verify identity and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.