Description

3-Bromo-2-Butoxy-5-Fluorophenylboronic is a specialized organoboron compound, a key building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation, a critical step in constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing complex fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the unique halogenated structure imparts specific biological activity.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid partner for palladium-catalyzed cross-coupling, a fundamental method for creating biaryl and heterobiaryl structures.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where fluorinated phenylboronic acids can tune electronic properties.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the creation of molecular probes and sensors for studying biological processes due to its reactive boronic acid functional group.

Basic Information

Product Name	3-Bromo-2-Butoxy-5-Fluorophenylboronic
CAS No.	352534-85-1
Molecular Formula	C10H13BBrFO3
Molecular Weight	290.93 g/mol
Synonyms	(3-Bromo-2-butoxy-5-fluorophenyl)boronic acid; 2-Butoxy-3-bromo-5-fluorobenzeneboronic acid; 3-Bromo-2-butoxy-5-fluorobenzeneboronic acid; Boronic acid, B-(3-bromo-2-butoxy-5-fluorophenyl)-; 352534-85-1; 3-Bromo-2-butoxy-5-fluorophenylboronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Butoxy-5-Fluorophenylboronic is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.