Description

3-Bromo-2-Fluoro-2-Isopropoxyphenyl- is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated aromatic structure. This compound matters for its critical role as a versatile building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in drug discovery and development pipelines. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromo and fluoro substituents for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in areas targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the bromo-fluoro motif can enhance efficacy and environmental profile.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials requiring specific halogenated aromatic units.
• Chemical Biology & Proteomics: Can be utilized as a molecular probe or a tag in bioconjugation chemistry due to its reactive halogen site.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Bromo-2-Fluoro-2-Isopropoxyphenyl-
CAS No.	352534-84-0
Molecular Formula	C9H10BrFO
Molecular Weight	233.08 g/mol
Synonyms	2-Isopropoxy-3-bromo-2-fluorobenzene; 1-Bromo-2-fluoro-3-isopropoxybenzene; 3-Bromo-2-fluoroanisole, isopropoxy derivative; Benzene, 1-bromo-2-fluoro-3-(1-methylethoxy)-; 352534-84-0; 3-Bromo-2-fluoro-2-isopropoxybenzene; 2-Fluoro-3-bromo-1-isopropoxybenzene
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluoro-2-Isopropoxyphenyl- is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.