Description

3-Bromo-2-Ethoxy-5-Fluorophenylboronicacid is a high-purity, multi-functional boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly in the development of active pharmaceutical ingredients (APIs) and novel organic electronic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, especially those containing fluorinated and brominated aromatic systems for enhanced bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the specific halogen and ether substitutions can fine-tune biological activity and environmental persistence.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors that leverage boronic acid's affinity for diols, useful in carbohydrate recognition and detection.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs specializing in providing bespoke organic compounds for client R&D projects.

Basic Information

Item	Details
Product Name	3-Bromo-2-Ethoxy-5-Fluorophenylboronicacid
CAS No.	352534-82-8
Molecular Formula	C8H9BBrFO3
Molecular Weight	262.87 g/mol
Synonyms	(3-Bromo-2-ethoxy-5-fluorophenyl)boronic acid; 3-Bromo-2-ethoxy-5-fluorobenzeneboronic acid; 2-Ethoxy-3-bromo-5-fluorophenylboronic acid; Boronic acid, B-(3-bromo-2-ethoxy-5-fluorophenyl)-; 352534-82-8; 3-Br-2-EtO-5-F-PhB(OH)2
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Ethoxy-5-Fluorophenylboronicacid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically reporting purity by HPLC/NMR, identity confirmation, and levels of key impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.