Description

2-Fluoro-5-Formylphenylboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl and a boronic acid group on a fluorinated aromatic ring, makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as Suzuki-Miyaura cross-coupling and as a precursor for more elaborate functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring fluorinated biaryl structures.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boron-containing coupling partner for the formation of carbon-carbon bonds, essential for creating complex organic molecules.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides where the fluorine atom and boronic acid group impart specific biological activity and stability.
• Ligand and Catalyst Development: Employed as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Utilized in the development of organic electronic materials, polymers, and liquid crystals due to its functional handles for further chemical modification.
• Chemical Biology Probes: Acts as a building block for synthesizing molecular probes and sensors that target specific biological processes.

Basic Information

Product Name	2-Fluoro-5-Formylphenylboronic Acid
CAS No.	352534-79-3
Molecular Formula	C7H6BFO3
Molecular Weight	167.93 g/mol
Synonyms	(2-Fluoro-5-formylphenyl)boronic acid; 5-Borono-2-fluorobenzaldehyde; 2-Fluoro-5-formylbenzeneboronic acid; 2-Fluoro-5-carboxaldehydephenylboronic acid; 2-Fluorobenzaldehyde-5-boronic acid; 5-Formyl-2-fluorophenylboronic acid; 2-Fluoro-5-formylphenyl-B(OH)2; Aldehyde-functionalized fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Formylphenylboronic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Comprehensive analytical methods including HPLC, NMR, and IR spectroscopy are employed to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.