Description

trans-2-(4-(Trifluoromethyl)Phenyl)- is a high-purity, advanced pharmaceutical intermediate characterized by its specific aromatic trifluoromethyl substitution. This compound is critical for its role in modulating the physicochemical properties of target molecules, enhancing metabolic stability and bioavailability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the trifluoromethyl group contributes to improved efficacy and environmental profile.
• Material Science: Serves as a precursor for specialty monomers and ligands used in advanced polymers and metal-organic frameworks (MOFs).
• Liquid Crystal & OLED Materials: A valuable synthon for creating fluorinated aromatic cores essential in electronic display and lighting technologies.
• Academic & R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	trans-2-(4-(Trifluoromethyl)Phenyl)-
CAS No.	352525-91-8
Molecular Formula	C9H5F3
Molecular Weight	170.13 g/mol
Synonyms	2-(4-(Trifluoromethyl)phenyl)ethene; 1-Ethenyl-4-(trifluoromethyl)benzene; 4-Vinylbenzotrifluoride; 4-Trifluoromethylstyrene; p-Trifluoromethylstyrene; (4-Trifluoromethylphenyl)ethylene; 4-Vinyl-α,α,α-trifluorotoluene; 4-(Trifluoromethyl)styrene
EINECS	Contact for details

Quality Control

Every batch of trans-2-(4-(Trifluoromethyl)Phenyl)- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.