Description

3-Bromo-5-Fluoro-2-Methoxyphenylboronic acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates containing complex biaryl structures.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific halogenated aromatic motifs.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and other advanced synthetic methodologies.
• Chemical Biology & Probe Synthesis: Utilized for constructing molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Bromo-5-Fluoro-2-Methoxyphenylboronic acid
CAS No.	352525-85-0
Molecular Formula	C7H7BBrFO3
Molecular Weight	248.85 g/mol
Synonyms	(3-Bromo-5-fluoro-2-methoxyphenyl)boronic acid; 2-Methoxy-3-bromo-5-fluorophenylboronic acid; 3-Bromo-5-fluoro-2-methoxybenzeneboronic acid; Boronic acid, B-(3-bromo-5-fluoro-2-methoxyphenyl)-; 352525-85-0; 3-Bromo-5-fluoro-o-anisylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Fluoro-2-Methoxyphenylboronic acid is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.