Description

Benzylpenicillinate-D7, Potassium Salt is a high-purity, deuterium-labeled internal standard critical for advanced analytical chemistry. This compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses, particularly in regulated environments. It is primarily used by pharmaceutical researchers, contract research organizations (CROs), and analytical laboratories for method development, pharmacokinetic studies, and quality control of penicillin-related substances.

Application

• Quantitative Mass Spectrometry (LC-MS/MS, GC-MS): Serves as a stable isotope-labeled internal standard for the precise quantification of benzylpenicillin and its metabolites in complex biological matrices.
• Pharmaceutical R&D: Used in method development and validation for drug metabolism and pharmacokinetics (DMPK) studies of penicillin antibiotics.
• Bioanalytical Testing: Enables accurate measurement of drug concentrations in plasma, serum, and tissue samples for clinical and pre-clinical trials.
• Residue Analysis: Applied in food safety and environmental testing to detect and quantify penicillin residues with high specificity and sensitivity.
• Metabolite Identification: Aids in the structural elucidation and tracking of penicillin-derived metabolites in in vitro and in vivo studies.
• Quality Control & Assurance: Supports impurity profiling and assay verification of penicillin active pharmaceutical ingredients (APIs) and finished drug products.

Basic Information

Product Name	Benzylpenicillinate-D7, Potassium Salt
CAS No.	352323-25-2
Molecular Formula	C16D7H11KN2O4S
Molecular Weight	372.48 g/mol
Synonyms	Potassium (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenyl-d5-carbonyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate-2-d2; Benzylpenicillin-d7 Potassium Salt; Penicillin G-d7 Potassium Salt; [Phenyl-d5]-Penicillin G Potassium Salt-2-d2; Potassium Penicillin-d7 G; Deuterated Penicillin G Potassium Salt
EINECS	Contact for details

Quality Control

Every batch of Benzylpenicillinate-D7, Potassium Salt is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity to meet the exacting demands of analytical reference standards. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, isotopic enrichment, and purity by HPLC and NMR. Our quality commitment aligns with the standards expected for cGMP and ISO 17034 reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.