Description

2-Fluoro-3-Methoxyphenylboronic Acid is a versatile organoboron building block essential for modern synthetic chemistry. This compound matters for its crucial role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone method for forming carbon-carbon bonds. Pharmaceutical, agrochemical, and advanced materials researchers need it for the efficient synthesis of complex, fluorinated aromatic target molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a fluorinated aromatic scaffold.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the 2-fluoro-3-methoxy moiety imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics.
• Chemical Biology Probes: Utilized to create fluorinated analogs of biomolecules for studying biological pathways and protein-ligand interactions.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical suppliers and CROs/CMOs offering bespoke synthesis services.

Basic Information

Item	Detail
Product Name	2-Fluoro-3-Methoxyphenylboronic Acid
CAS No.	352303-67-4
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(2-Fluoro-3-methoxyphenyl)boronic acid; 2-Fluoro-3-methoxybenzeneboronic acid; 3-Methoxy-2-fluorophenylboronic acid; 2-Fluoro-m-anisylboronic acid; Boronic acid, B-(2-fluoro-3-methoxyphenyl)-; 352303-67-4; (2-Fluoro-3-methoxyphenyl)boronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-3-Methoxyphenylboronic Acid is produced under strict quality management protocols. We ensure compliance with relevant industry standards, and our rigorous analytical testing includes HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.