Description

Stresscopin Human is a synthetic peptide analog of the endogenous human corticotropin-releasing hormone (CRH), also known as urocortin, with the CAS registry number 352020-03-2. This compound is of significant interest for its role in the hypothalamic-pituitary-adrenal (HPA) axis and its potential as a critical research tool in neuroendocrinology and stress physiology. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on stress-related disorders, metabolic pathways, and central nervous system (CNS) drug discovery.

Application

• Biomedical Research: Fundamental studies on the HPA axis, stress response mechanisms, and neuroendocrine signaling pathways.
• Drug Discovery & Development: Screening for CRH receptor (CRHR1/CRHR2) agonists/antagonists and preclinical evaluation of compounds targeting stress, anxiety, and depression.
• Diagnostic Assay Development: Use as a reference standard or calibrator in immunoassays (ELISA, RIA) for quantifying related biomarkers.
• Pharmacological Studies: Investigating the physiological effects of urocortin peptides on cardiovascular function, appetite regulation, and gastrointestinal activity.
• Academic & Clinical Research: Exploring the role of corticotropin-releasing factors in inflammatory conditions, addiction, and metabolic syndromes.

Basic Information

Product Name	Stresscopin Human
CAS No.	352020-03-2
Molecular Formula	C₁₉₈H₃₁₀N₅₆O₅₈S
Molecular Weight	4430.8 g/mol
Synonyms	Human Urocortin; Urocortin, human; UCN; hUCN; Stresscopin; Corticotropin-Releasing Hormone Peptide (Urocortin); CRH-related peptide; Sauvagine (related); [Ser²⁹,Ser⁴⁰,Leu⁷¹]Sauvagine(29-71)-amide
EINECS	Contact for details

Quality Control

Our Stresscopin Human is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A detailed Certificate of Analysis (COA) is provided, documenting purity, peptide content, and solvent residues. We support research requiring compliance with relevant standards and can provide material suitable for use as a pharmaceutical reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.