Description

6-Fluoro-3(2H)-Benzofuranone is a fluorinated benzofuranone derivative, a versatile and valuable fluorinated building block in advanced organic synthesis. Its core value lies in its ability to introduce both the benzofuranone scaffold and a fluorine atom, enabling the development of novel compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients, as well as by fine chemical manufacturers producing specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can improve metabolic stability, bioavailability, and binding affinity.
• Material Science Research: Serves as a precursor for developing novel fluorinated organic materials, including liquid crystals, polymers, and organic electronic components.
• Chemical Biology & Proteomics: Employed as a building block for synthesizing fluorinated probes and tags used in bioimaging and studying biological processes.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, specialty fluorinated compounds.

Basic Information

Product Name	6-Fluoro-3(2H)-Benzofuranone
CAS No.	351528-80-8
Molecular Formula	C8H5FO2
Molecular Weight	152.12 g/mol
Synonyms	6-Fluorobenzofuran-3(2H)-one; 6-Fluoro-2,3-dihydro-1-benzofuran-3-one; 6-Fluoro-3-hydroxybenzofuran; 6-Fluoro-3-oxo-2,3-dihydrobenzofuran; 2,3-Dihydro-6-fluorobenzofuran-3-one; 6-Fluorodihydrobenzofuran-3-one; 351528-80-8
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3(2H)-Benzofuranone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ISO standards for reliable integration into your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.