Description

Phenylalanine, 4-Amino-n-[(1,1-Dimethylethoxy)Carbonyl]- is a protected amino acid derivative, specifically a Boc-protected phenylalanine analog, which is essential for advanced peptide synthesis and pharmaceutical research. This compound matters because it provides a crucial building block for creating complex peptides and active pharmaceutical ingredients (APIs) with high stereochemical purity and minimal side reactions. It is primarily needed by research institutions, pharmaceutical development labs, and fine chemical manufacturers engaged in the production of therapeutic peptides, peptidomimetics, and novel drug candidates.

Application

• Peptide Synthesis: A key intermediate in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled incorporation of modified phenylalanine residues.
• Pharmaceutical Intermediates: Serves as a critical precursor in the research and development of novel peptide-based therapeutics and APIs.
• Bioconjugation & Probe Development: Used in the synthesis of labeled peptides for biochemical assays, diagnostic probes, and targeted drug delivery systems.
• Academic & Industrial R&D: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and the development of peptidomimetics.
• Process Chemistry: Utilized in scale-up and process optimization for the commercial manufacturing of specialty peptides.

Basic Information

Product Name	Phenylalanine, 4-Amino-n-[(1,1-Dimethylethoxy)Carbonyl]-
CAS No.	351208-73-6
Molecular Formula	C₁₄H₂₀N₂O₄
Molecular Weight	280.32 g/mol
Synonyms	Boc-4-Amino-L-phenylalanine; N-Boc-4-Amino-L-phenylalanine; (2S)-2-[(tert-Butoxycarbonyl)amino]-4-aminobutanoic Acid (Phenylalanine derivative); tert-Butyl (4-amino-1-carboxy-3-phenylpropyl)carbamate; 4-Amino-N-Boc-L-phenylalanine; Boc-Phe(4-NH2)-OH; Fmoc-Phe(4-NH-Boc)-OH (related protected form); 4-Aminophenylalanine Boc derivative
EINECS	Contact for details

Quality Control

Our Phenylalanine, 4-Amino-n-[(1,1-Dimethylethoxy)Carbonyl]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant and inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.