Description

4-Ethoxy-2',3',4',5',6'-Pentafluorobenzophenone is a specialized fluorinated aromatic ketone building block, identified by CAS No. 351003-31-1. This compound is valued for its unique molecular architecture, which combines an ethoxy-substituted pentafluorophenyl ring with a benzophenone core, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules where fluorine substitution is key to modulating biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the pentafluorophenyl group enhances lipophilicity and environmental stability.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a photoaffinity labeling probe or a scaffold for designing enzyme inhibitors due to the photoreactive benzophenone moiety.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, nucleophilic aromatic substitution, and as a directing group in metal-catalyzed transformations for academic and industrial research.

Basic Information

Product Name	4-Ethoxy-2',3',4',5',6'-Pentafluorobenzophenone
CAS No.	351003-31-1
Molecular Formula	C15H9F5O2
Molecular Weight	316.23 g/mol
Synonyms	4-Ethoxy-2,3,4,5,6-pentafluorobenzophenone; 2,3,4,5,6-Pentafluoro-4'-ethoxybenzophenone; 1-(4-Ethoxyphenyl)-2,3,4,5,6-pentafluorophenylmethanone; Benzophenone, 4-ethoxy-2,3,4,5,6-pentafluoro-; (4-Ethoxyphenyl)(pentafluorophenyl)methanone
EINECS	Contact for details

Quality Control

Our 4-Ethoxy-2',3',4',5',6'-Pentafluorobenzophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.