Description

4-Ethynylphenylacetonitrile is a versatile and high-purity organic building block featuring both an acetonitrile and an ethynyl functional group on a phenyl ring. This unique bifunctional structure makes it a critical intermediate for synthesizing advanced materials and complex pharmaceutical molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced organic electronic materials.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new organic reactions and constructing complex heterocycles via click chemistry and Sonogashira coupling.
• Liquid Crystal & OLED Development: Acts as a core synthon for creating novel organic semiconductors and emissive materials for display technologies.

Basic Information

Product Name	4-Ethynylphenylacetonitrile
CAS No.	351002-90-9
Molecular Formula	C10H7N
Molecular Weight	141.17 g/mol
Synonyms	4-Ethynylbenzeneacetonitrile; (4-Ethynylphenyl)acetonitrile; 2-(4-Ethynylphenyl)acetonitrile; p-Ethynylphenylacetonitrile; 4-Cyanomethylphenylacetylene; 4-(Cyanomethyl)phenylacetylene; 1-(Cyanomethyl)-4-ethynylbenzene; Benzeneacetonitrile, 4-ethynyl-
EINECS	Contact for details

Quality Control

Our 4-Ethynylphenylacetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure a typical purity of ≥97% and conformity to agreed specifications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	< 0.5%
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.