Description

Boc- -(4-Methylbenzyl)-Dl-Pro-Oh is a protected amino acid derivative featuring a tert-butoxycarbonyl (Boc) group and a 4-methylbenzyl side chain. This compound serves as a crucial chiral building block in the synthesis of complex peptides and peptidomimetics, offering versatility for advanced organic transformations. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, process development, and the production of fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic peptides and small molecule drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) for constructing peptide chains with specific structural features.
• Protease Inhibitor Research: Acts as a precursor or core structure in the design and synthesis of protease enzyme inhibitors.
• Chemical Biology Probes: Employed in the creation of labeled or modified peptides for studying protein-protein interactions and cellular processes.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in catalytic asymmetric reactions to introduce chirality.
• Fine Chemical Production: Serves as a specialized intermediate in the custom synthesis of high-value, complex organic molecules.

Basic Information

Product Name	Boc- -(4-Methylbenzyl)-Dl-Pro-Oh
CAS No.	351002-82-9
Molecular Formula	C₁₈H₂₅NO₄
Molecular Weight	319.40 g/mol
Synonyms	1-[(4-Methylphenyl)methyl]-N-[(1,1-dimethylethoxy)carbonyl]-DL-proline; N-Boc-1-(4-Methylbenzyl)-DL-proline; N-(tert-Butoxycarbonyl)-1-(4-methylbenzyl)-DL-proline; tert-Butyl 1-(4-methylbenzyl)-DL-prolinate; Boc-1-(p-Methylbenzyl)-DL-proline; DL-1-(4-Methylbenzyl)proline N-Boc derivative; N-Boc-1-(p-Tolylmethyl)-DL-proline
EINECS	Contact for details

Quality Control

Our Boc- -(4-Methylbenzyl)-Dl-Pro-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	DL-mixture (Racemic)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.