Description

2-(Chloromethyl)-5-(4-Fluorophenyl)-1,3,4-Oxadiazole is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the oxadiazole core.
• Material Science Research: Serves as a building block for creating functional polymers, liquid crystals, and organic electronic materials due to its rigid, aromatic structure.
• Chemical Biology & Proteomics: Employed in the design and synthesis of activity-based probes (ABPs) and molecular tags for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on various scales.

Basic Information

Product Name	2-(Chloromethyl)-5-(4-Fluorophenyl)-1,3,4-Oxadiazole
CAS No.	350672-14-9
Molecular Formula	C9H6ClFN2O
Molecular Weight	212.61 g/mol
Synonyms	5-(4-Fluorophenyl)-2-(chloromethyl)-1,3,4-oxadiazole; 2-Chloromethyl-5-(4-fluorophenyl)-1,3,4-oxadiazole; 1,3,4-Oxadiazole, 2-(chloromethyl)-5-(4-fluorophenyl)-; (4-Fluorophenyl)-5-(chloromethyl)-1,3,4-oxadiazole; 350672-14-9; FC6H4C2N2OCH2Cl
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-5-(4-Fluorophenyl)-1,3,4-Oxadiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.