Description

Rat IL-10 is a high-purity recombinant protein designed for critical life science research and development. This product is essential for studying the immunomodulatory functions of interleukin-10 in rodent models, providing researchers with a reliable and consistent biological reagent. It is primarily utilized by scientists in the fields of immunology, inflammation research, and preclinical drug discovery for applications such as cell culture, bioassay development, and in vivo studies.

Application

• Immunological Research: Used to study the anti-inflammatory and immunosuppressive roles of IL-10 in rodent models of autoimmune disease, infection, and cancer.
• Cell Culture & Differentiation: Acts as a key cytokine for the in vitro generation, maintenance, and functional modulation of regulatory T cells (Tregs) and other immune cell populations.
• Bioassay Standard & Development: Serves as a critical standard or stimulant in ELISA, cell-based proliferation assays, and other quantitative bioanalytical methods.
• Preclinical Drug Discovery: Employed in target validation and efficacy testing for therapeutic candidates aimed at modulating the IL-10 signaling pathway.
• Inflammation Modeling: Applied in experimental setups to investigate the resolution of inflammation and tissue repair mechanisms.
• Reagent for Antibody Validation: Used as a positive control or coating antigen to validate the specificity of anti-IL-10 antibodies in various immunoassays.

Basic Information

Product Name	Rat IL-10
CAS No.	350590-73-7
Molecular Formula	Contact for details
Molecular Weight	~18-20 kDa (monomer, glycosylated form)
Synonyms	Rat Interleukin-10; rRtIL-10; Recombinant Rat IL-10; Rat Cytokine Synthesis Inhibitory Factor (CSIF); Rat IL10; Interleukin-10 (Rat); Rat IL-10 Protein; TGIF (Rat)
EINECS	Contact for details

Quality Control

Our Rat IL-10 is produced under stringent conditions and undergoes rigorous quality testing to ensure high biological activity, purity, and consistency. Each batch is tested for identity, purity, endotoxin level, and functional activity in standardized bioassays. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep the lyophilized powder at -20°C or below. Upon reconstitution, aliquot and store at -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive).

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Purity (SDS-PAGE)	> 95%
Identification (Mass Spec)	Consistent with Rat IL-10
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity (Cell Proliferation)	Contact for details
Solubility	Soluble in sterile PBS or cell culture medium

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.