Description

n-Boc-3,5-Dibromo-Dl-Tyrosine is a protected, halogenated derivative of the amino acid tyrosine, serving as a crucial synthetic intermediate in advanced organic chemistry. Its primary value lies in providing a versatile building block for the construction of complex peptides and bioactive molecules, where the tert-butoxycarbonyl (Boc) protecting group offers orthogonal deprotection strategies. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly in the synthesis of novel drug candidates, peptide mimetics, and specialized biochemical probes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel peptide-based therapeutics and drug candidates.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate brominated tyrosine residues.
• Bioconjugation & Probe Development: Serves as a precursor for creating fluorescent or radioactive probes for biological imaging and assay development.
• Chemical Biology Research: Employed in studying protein-protein interactions and enzyme mechanisms by introducing halogen atoms for structure-activity relationship (SAR) studies.
• Material Science: Potential monomer or precursor for designing functional polymers and biomaterials with specific halogen-related properties.
• Agrochemical Research: Intermediate in the development of new crop protection agents and bioactive compounds.

Basic Information

Product Name	n-Boc-3,5-Dibromo-Dl-Tyrosine
CAS No.	349535-07-5
Molecular Formula	C₁₄H₁₇Br₂NO₅
Molecular Weight	447.10 g/mol
Synonyms	Boc-3,5-Dibromo-DL-tyrosine; (RS)-2-((tert-Butoxycarbonyl)amino)-3-(3,5-dibromo-4-hydroxyphenyl)propanoic acid; 3,5-Dibromo-N-(tert-butoxycarbonyl)tyrosine; DL-3,5-Dibromo-N-Boc-tyrosine; tert-Butyl (3,5-dibromo-4-hydroxyphenyl)alaninate; N-Boc-3,5-dibromotyrosine; Boc-DL-Tyr(3,5-Br₂)-OH
EINECS	Contact for details

Quality Control

Our n-Boc-3,5-Dibromo-Dl-Tyrosine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.