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4-Fluoro-n-Propylbenzamide CAS NO 349129-65-3
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CAS No.:349129-65-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-Fluoro-n-Propylbenzamide is a specialized fluorinated aromatic amide building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate a fluoro-substituted benzamide moiety into their target molecules.
Application
- Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and metabolic diseases.
- Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom enhances lipophilicity and biological activity.
- Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
- Chemical Biology Probe Synthesis: Employed to create labeled compounds or molecular probes for studying biological pathways and protein interactions.
- Polymer Modification: Acts as a monomer or modifier to introduce fluorine-containing side chains into polymers, altering their physical and chemical properties.
- Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring fluorinated intermediates.
Basic Information
| Item | Detail |
|---|---|
| Product Name | 4-Fluoro-n-Propylbenzamide |
| CAS No. | 349129-65-3 |
| Molecular Formula | C10H12FNO |
| Molecular Weight | 181.21 g/mol |
| Synonyms | 4-Fluoropropylbenzamide; p-Fluoropropylbenzamide; N-Propyl-4-fluorobenzamide; 4-Fluoro-N-propylbenzamide; 1-(4-Fluorophenyl)-1-oxopropan-2-amine (tautomeric form); 4-Fluorobenzoylpropylamine; FPB; 349129-65-3 (CAS Registry Number) |
| EINECS | Contact for details |
Quality Control
Our 4-Fluoro-n-Propylbenzamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | < 10 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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