Description

3-Chloro-n-(2-Fluorophenyl)Propanamide is a specialized organic building block featuring a propanamide backbone substituted with chloro and fluorophenyl groups. This compound matters as a key intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its unique halogenated structure enables precise modifications to target properties. It is primarily needed by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring specific halogenated pharmacophores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine and chlorine substituents can enhance biological activity and environmental stability.
• Organic Synthesis: Serves as a versatile precursor for further chemical transformations, including amide coupling, nucleophilic substitution, and cyclization reactions to create more complex heterocyclic systems.
• Material Science: Potential intermediate in the production of specialty polymers, liquid crystals, or organic electronic materials that benefit from its aromatic and amide functionalities.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical manufacturing.

Basic Information

Product Name	3-Chloro-n-(2-Fluorophenyl)Propanamide
CAS No.	349097-66-1
Molecular Formula	C9H9ClFNO
Molecular Weight	201.63 g/mol
Synonyms	3-Chloro-N-(2-fluorophenyl)propanamide; N-(2-Fluorophenyl)-3-chloropropanamide; 3-Chloropropanamide, N-(2-fluorophenyl)-; Propanamide, 3-chloro-N-(2-fluorophenyl)-; 349097-66-1; 2-Fluoro-3'-chloropropionanilide; 3-Chloro-N-(o-fluorophenyl)propanamide
EINECS	Contact for details

Quality Control

Our 3-Chloro-n-(2-Fluorophenyl)Propanamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.